An artificial intelligence (AI) tool has emerged to assist doctors in combating aggressive brain tumors. It aids in identifying crucial characteristics that provide guidance during surgery.
The Cryosection Histopathology Assessment and Review Machine (Charm) is an advanced tool that efficiently analyzes images to identify the genetic profile of gliomas, a type of aggressive brain tumor. Currently, this process takes days or weeks. Kun-Hsing Yu, the senior author of a July 7 report in Med, explained that surgeons rely on detailed diagnoses to guide their operations.
Although the tool’s accuracy cannot match current genetic tests, it can swiftly predict a tumor’s profile. This quick analysis enables doctors to proceed with appropriate treatment without needing to schedule and perform additional surgeries, saving valuable time, explained Yu.
In addition, Charm can distinguish between malignant and benign tumor cells and determine the tumor’s grade, indicating its level of aggressiveness. These are assessments that human pathologists typically make during surgery. However, according to Yu, Charm could eliminate the need for a 10-to-15-minute wait or the presence of a pathologist on standby during the operation.
Glioma — particularly the aggressive subtype known as glioblastoma — poses a significant threat, with untreated cases leading to death in less than six months. Tragically, only 17% of individuals diagnosed with glioblastoma survive beyond the second year, according to the American Association of Neurological Surgeons.
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Author: Amaka Nwaokocha
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